Drug trials, the "elderly", and the very aged

Does primary Streptococcus viridans pneumonia exist?

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·1992

Acyl-CoA:cholesterol O-acyl transferase (ACAT) inhibitors. 1. 2-(Alkylthio)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.

Journal of medicinal chemistry·1992

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite.

Archives of biochemistry and biophysics·1992

Evaluation of new anti-infective drugs for the treatment of infective endocarditis. Infectious Diseases Society of America and the Food and Drug Administration.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·1992

Screening for alpha-thalassemia. Correlation of hemoglobin H inclusion bodies with DNA-determined genotype.

Archives of pathology & laboratory medicine·1992

Parent gender, victim gender, and family socioeconomic level influences on the potential reporting by nurses of physical child abuse.

Issues in comprehensive pediatric nursing·1992

1-month versus 12-month dual antithrombotic therapy after percutaneous coronary intervention in patients with atrial fibrillation (OPTIMA-AF): a multicentre, open-label, hybrid non-inferiority and superiority, randomised, controlled trial.

Lancet (London, England)·2026

Multidomain lifestyle intervention for the prevention of cognitive decline in at-risk older adults in Latin America (LatAm-FINGERS): a single-blind, multicentre, randomised controlled trial.

Lancet (London, England)·2026

Advancing the relevance of clinical trials for older patients.

Lancet (London, England)·2026

Temocillin versus carbapenems for bacteraemia due to third-generation cephalosporin-resistant Enterobacterales in Spain (ASTARTÉ): a multicentre, phase 3, open-label, non-inferiority, randomised clinical trial.

Lancet (London, England)·2026

Fixed-duration pirtobrutinib plus venetoclax-rituximab versus venetoclax-rituximab for patients with previously treated chronic lymphocytic leukaemia or small lymphocytic lymphoma (BRUIN CLL-322): an open-label, multicentre, randomised, controlled, phase 3 trial.

Lancet (London, England)·2026

Children in all policies: lessons from a global collaboration to promote the health and wellbeing of children and future generations.

Lancet (London, England)·2026

Exploring the Distinct Regulatory Actions and Molecular Pathways of Coptisine Through Network Pharmacology: Insights Into Its Influence on Platelet Activation and Thrombus Development.

Food science & nutrition·2026

Effect of Betahistine on Daytime Sedation and Metabolic Parameters in Patients with Schizophrenia on Second-generation Antipsychotics.

Indian journal of psychological medicine·2026

Adult dual and polytobacco use in the United States: Findings from the 2021-2023 National Survey on Drug Use and Health.

Preventive medicine reports·2026

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Versus Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Following Orthopedic Shoulder Surgery: A Comparative Analysis.

Cureus·2026

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Are Associated With Reduced Early but Increased Chronic Postoperative Opioid Use After Shoulder Surgery.

Cureus·2026

Simvastatin modulates sleep-wake behavior and locomotor activity in a dose-dependent manner in Drosophila.

Frontiers in pharmacology·2026

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Does primary Streptococcus viridans pneumonia exist?

Acyl-CoA:cholesterol O-acyl transferase (ACAT) inhibitors. 1. 2-(Alkylthio)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite.

Evaluation of new anti-infective drugs for the treatment of infective endocarditis. Infectious Diseases Society of America and the Food and Drug Administration.

Screening for alpha-thalassemia. Correlation of hemoglobin H inclusion bodies with DNA-determined genotype.

Parent gender, victim gender, and family socioeconomic level influences on the potential reporting by nurses of physical child abuse.

1-month versus 12-month dual antithrombotic therapy after percutaneous coronary intervention in patients with atrial fibrillation (OPTIMA-AF): a multicentre, open-label, hybrid non-inferiority and superiority, randomised, controlled trial.

Multidomain lifestyle intervention for the prevention of cognitive decline in at-risk older adults in Latin America (LatAm-FINGERS): a single-blind, multicentre, randomised controlled trial.

Advancing the relevance of clinical trials for older patients.

Temocillin versus carbapenems for bacteraemia due to third-generation cephalosporin-resistant Enterobacterales in Spain (ASTARTÉ): a multicentre, phase 3, open-label, non-inferiority, randomised clinical trial.

Fixed-duration pirtobrutinib plus venetoclax-rituximab versus venetoclax-rituximab for patients with previously treated chronic lymphocytic leukaemia or small lymphocytic lymphoma (BRUIN CLL-322): an open-label, multicentre, randomised, controlled, phase 3 trial.

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Exploring the Distinct Regulatory Actions and Molecular Pathways of Coptisine Through Network Pharmacology: Insights Into Its Influence on Platelet Activation and Thrombus Development.

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Adult dual and polytobacco use in the United States: Findings from the 2021-2023 National Survey on Drug Use and Health.

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Versus Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Following Orthopedic Shoulder Surgery: A Comparative Analysis.

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Simvastatin modulates sleep-wake behavior and locomotor activity in a dose-dependent manner in Drosophila.

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