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Related Experiment Videos

[Basic diet in Crohn's disease].

B Stober, W Nützenadel, F Ullrich

    Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
    |October 1, 1983
    PubMed
    Summary

    Children with Crohn's disease showed improved weight gain and reduced inflammation with an elementary diet. This dietary approach, combined with sulfasalazine, offered significant benefits over steroid treatment for pediatric Crohn's disease patients.

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    [Hypertrophic pyloric stenosis: sonographic monitoring of conservative therapy with intravenous atropine sulfate].

    Ultraschall in der Medizin (Stuttgart, Germany : 1980)·2000

    Area of Science:

    • Pediatric Gastroenterology
    • Inflammatory Bowel Disease Research
    • Nutritional Therapy in Children

    Background:

    • Crohn's disease is a chronic inflammatory bowel disease affecting children.
    • Current treatments for active Crohn's disease in children include steroids and sulfasalazine.
    • The role of exclusive or combined elementary diet in pediatric Crohn's disease management requires further investigation.

    Purpose of the Study:

    • To evaluate the efficacy of an elementary diet, with or without steroids and sulfasalazine, in treating acute pediatric Crohn's disease.
    • To compare the effects of different treatment regimens on clinical and biochemical parameters in children with Crohn's disease.

    Main Methods:

    • A comparative study involving 26 children with acute Crohn's disease symptoms.
    • Three treatment groups: Group A (steroids + sulfasalazine), Group B (elementary diet + sulfasalazine), Group C (elementary diet + steroids + sulfasalazine).
    • Assessment of clinical outcomes (defecation frequency, body weight) and biochemical markers (sedimentation rate, plasma leukocytes, plasma total proteins).

    Main Results:

    • All groups showed decreased sedimentation rate and defecation frequency.
    • Group B (elementary diet + sulfasalazine) exhibited normalization of plasma leukocytes and significant body weight gain.
    • Group B and C showed significant weight gain, while Group A did not; Group A also had a decline in plasma total proteins.

    Conclusions:

    • An elementary diet is beneficial for children with active Crohn's disease, promoting significant weight gain.
    • The elementary diet, particularly when combined with sulfasalazine, appears more effective than steroid treatment for nutritional recovery and potentially inflammation control.
    • Further research into the long-term effects and mechanisms of elementary diet in pediatric Crohn's disease is warranted.

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