Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transient ischemic attacks: racial differences, treatment, and prognosis.

Y Tsuda, K Kimura, S Yoneda

    Neurological Research
    |January 1, 1983
    PubMed
    Summary

    Transient ischemic attack (TIA) patients with severe intracranial atherosclerosis face a poorer prognosis. Early stroke risk is higher after a single TIA episode, suggesting emboli play a role.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Stimulation of the hamster ventral lateral geniculate nucleus induces Fos-like immunoreactivity in suprachiasmatic nucleus cells.

    Neuroscience letters·1992
    Same author

    Papillary craniopharyngioma of the third ventricle--case report.

    Neurologia medico-chirurgica·1992
    Same author

    Sequential change of heterogeneous cerebral blood blow patterns after diffuse brain ischemia.

    Resuscitation·1992
    Same author

    Cerebral infarction in a heterozygote with variant antithrombin III.

    Stroke·1992
    Same author

    Ocular convergence-related neuronal responses in the lateral suprasylvian area of alert cats.

    Neuroscience research·1992
    Same author

    [Evaluation of cerebral blood circulation using fast magnetic resonance imaging (turbo-FLASH)].

    No shinkei geka. Neurological surgery·1992

    Area of Science:

    • Neurology
    • Vascular Medicine
    • Cerebrovascular Disease

    Background:

    • Transient ischemic attack (TIA) is a critical warning sign for future stroke.
    • Understanding TIA prognosis is essential for timely intervention and stroke prevention.
    • Cerebral atherosclerosis characteristics may differ across ethnicities, impacting TIA genesis.

    Purpose of the Study:

    • To investigate the prognosis of transient ischemic attack (TIA) in a cohort of Japanese patients.
    • To identify clinical and angiographic factors associated with stroke progression after TIA.
    • To compare the effectiveness of different treatment modalities for TIA.

    Main Methods:

    • Prospective investigation of 45 patients diagnosed with TIA over an average follow-up of 12.9 months.

    Related Experiment Videos

  • Angiographic examination of 29 patients to assess the severity and location of atherosclerotic lesions.
  • Comparison of stroke progression rates based on lesion severity, location, TIA recurrence, and treatment.

    • Main Results:

    • 27% of TIA patients progressed to complete stroke during the follow-up period.
    • Severe intracranial atherosclerotic lesions, particularly those involving both intracranial and extracranial arteries, were associated with a poorer prognosis.
    • A single prior TIA episode significantly increased the risk of early stroke (57% progression rate).
    • Superficial temporal artery to middle cerebral artery anastomosis and anticoagulant therapy appeared more beneficial than antiplatelet aggregation therapy.

    Conclusions:

    • Severe intracranial atherosclerosis is a significant risk factor for stroke progression after TIA in the Japanese population.
    • The findings suggest potential ethnic differences in the pathogenesis of cerebral atherosclerosis.
    • Embolus formation from arterial lesions is implicated in the pathogenesis of TIA and subsequent stroke.
    • Surgical or anticoagulant treatments may offer better TIA prognosis compared to antiplatelet therapy.