Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neuromuscular recovery after laparoscopy.

R J Fragen, C A Shanks

    Anesthesia and Analgesia
    |January 1, 1984
    PubMed
    Summary

    Vecuronium bromide offers faster recovery than pancuronium for laparoscopic surgery, making it easier to reverse muscle blockade. This leads to better outcomes and easier patient discharge after gynecologic procedures.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A comparison of the SNAP II and BIS XP indices during sevoflurane and nitrous oxide anaesthesia at 1 and 1.5 MAC and at awakening.

    British journal of anaesthesia·2006
    Same author

    Clinical delineation and localization to chromosome 9p13.3-p12 of a unique dominant disorder in four families: hereditary inclusion body myopathy, Paget disease of bone, and frontotemporal dementia.

    Molecular genetics and metabolism·2001
    Same author

    The pharmacokinetics of dexmedetomidine in volunteers with severe renal impairment.

    Anesthesia and analgesia·2001
    Same author

    Impact of the initial doses of rocuronium and pancuronium on subsequent maintenance for neuromuscular block.

    Canadian journal of anaesthesia = Journal canadien d'anesthesie·2001
    Same author

    Isoflurane alters the recirculatory pharmacokinetics of physiologic markers.

    Anesthesiology·2000
    Same author

    Indocyanine green kinetics characterize blood volume and flow distribution and their alteration by propranolol.

    Clinical pharmacology and therapeutics·2000

    Area of Science:

    • Anesthesiology
    • Pharmacology

    Background:

    • Neuromuscular blocking agents are essential for surgical procedures requiring muscle relaxation.
    • Vecuronium bromide and pancuronium are commonly used agents with differing recovery profiles.

    Purpose of the Study:

    • To compare the efficacy and recovery characteristics of vecuronium bromide versus pancuronium for laparoscopic gynecologic surgery.
    • To evaluate the need for and ease of reversal of neuromuscular blockade.

    Main Methods:

    • A comparative study involving patients undergoing outpatient gynecologic laparoscopy.
    • Administration of vecuronium bromide (0.045 mg/kg) or pancuronium (0.07 mg/kg) for muscle relaxation.
    • Assessment of intubating conditions, abdominal relaxation, and neuromuscular recovery using train-of-four and clinical evaluation.

    Main Results:

    • Both vecuronium bromide and pancuronium provided adequate intubation and abdominal relaxation.
    • Spontaneous recovery was significantly faster with vecuronium bromide.
    • Pharmacological reversal was often unnecessary or easier to achieve with vecuronium bromide compared to pancuronium.
    • No significant differences in postoperative muscle power or coordination were observed between the groups.

    Conclusions:

    • Vecuronium bromide is a suitable alternative to pancuronium for laparoscopic gynecologic surgery, offering faster recovery and simpler reversal.
    • The choice of vecuronium bromide may facilitate smoother patient management and discharge on the same day.
    • Further research could explore optimal reversal strategies for pancuronium in specific patient populations.

    Related Experiment Videos