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Demethylation in vivo of a xanthine-related respiratory analeptic, ethimizol
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|November 1, 1983
Abstract:
Demethylation of ethimizol in humans yielded 1-ethyl-4-carbamoyl-5-methyl-carbamoylimidazole. The formation, and the excretion in urine or saliva, of the other mono-N-demethylated ethimizol isomer, 1-ethyl-5-carbamoyl-4-methylcarbamoylimidazole has not been detected.
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