[Allergic granulomatous angiitis (Churg-Strauss syndrome) manifested as polyneuritis. Its relation to panarteritis...

A 54 year old man with a history of resistant asthma presented with a multiple neuritis of subacute onset and hypereosinophilia. Histology showed necrotizing vasculitis with multinucleated giant cells compatible with Churg and Strauss' syndrome. Ultrastructural examination of nerves and immunopathological tests showed anti IgG serum fixing deposits in the arterial wall. Recovery was complete after corticoid therapy for 20 months. Literature on the Churg and Strauss' syndrome is reviewed and possible clinical, biologic, histopathologic, and physiopathologic relations between allergic granulomatous angiitis and panarteritis nodosa are discussed.