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Cytoskeletal studies on Lowicryl K4M embedded and Affi-Gel 731 attached rat peritoneal mast cells
Abstract:
The subplasmalemmal network in mast cells consists of irregularly arranged 6-7 nm filaments (actin) connected by thinner filaments. In places oblique filaments with crossbridges or short, perpendicular filaments (11-12 nm) connect cell and granule membrane. Filaments attaching subplasmalemmal network to cell membrane divide like a Y and attach cell membrane end-on with a conical, hook-like bending. Each granule is surrounded by a regular network of filaments.