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Kappa-opioid diuretic effects of tifluadom, a benzodiazepine opioid agonist
The Journal of Pharmacy and Pharmacology
|August 1, 1984
Abstract:
Tifluadom produced a dose-related (0.08-5 mg kg-1) diuresis in normally hydrated rats. This diuretic effect was antagonized by kappa-antagonist doses of naloxone and blocked by morphine administration. This is further in-vivo evidence that tifluadom is a fairly specific kappa-opioid agonist.
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