Renal amyloidosis and non-specific aorto-arteritis--a hitherto undescribed association

Two patients presented with the nephrotic syndrome complicating non-specific aorto-arteritis (Takayasu's arteritis). Histologically both had renal amyloidosis. On investigation there was no evidence of chronic infection or any immuno-inflammatory disease known to be associated with amyloidosis. These cases raise the possibility of a significant association between aorto-arteritis of the Takayasu type and systemic amyloidosis.