Taxol: an antimitotic agent with a new mechanism of action

Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase.

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Mdm2 selectively suppresses DNA damage arising from inhibition of topoisomerase II independent of p53.

Oncogene·2017

Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters.

Oncogene·2014

p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes.

Oncogene·2013

Peripheral blood mononuclear and tumor cell pharmacodynamics of the novel epothilone B analogue, ixabepilone.

Annals of oncology : official journal of the European Society for Medical Oncology·2006

Mutations in beta-tubulin map to domains involved in regulation of microtubule stability in epothilone-resistant cell lines.

Molecular cancer therapeutics·2002

Targeting KCC2 and NKCC1 for spinal motor dysfunction: pharmacology, therapeutic opportunities, and translational roadmap.

Pharmacology & therapeutics·2026

The regulatory and therapeutic potential of transposable elements in cancer and inflammatory diseases.

Pharmacology & therapeutics·2026

The rhythm of pressure: Circadian disruption and chronotherapy.

Pharmacology & therapeutics·2026

Drug resistance in cancer: Emerging mechanisms, translational barriers, and pharmacological strategies.

Pharmacology & therapeutics·2026

Neuroregulation as a modulatory force in immune checkpoint inhibitor resistance: mechanistic neuro-immune crosstalk informing biomarker-led diagnosis and targetable therapeutic sensitization.

Pharmacology & therapeutics·2026

Galectin-3 and its inhibitors: Overview and perspectives.

Pharmacology & therapeutics·2026

Synthesis of Chromones with Methylene-Bridged Carbon Substituent via Annulation of o-Hydroxyaryl Enaminones.

The Journal of organic chemistry·2026

Viburnum opulus protects against acetaminophen-induced splenic injury through coordinated antioxidant and anti-inflammatory responses.

Journal of molecular histology·2026

The oxysterolome iterative metabolism expands sterol signaling.

Trends in endocrinology and metabolism: TEM·2026

New benzylresorcinol and benzylstilbene derivatives from the fruits of orchid Galeola nudifolia Lour. with anti-neuroinflammatory activity.

RSC advances·2026

Isocoumarin Ring Rearrangement Approach to π-Extended Dibenzothiophenes.

The Journal of organic chemistry·2026

Torsion of a pedunculated accessory hepatic lobe: Cross-sectional imaging and histopathological correlation.

Journal of clinical imaging science·2026

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Taxol: an antimitotic agent with a new mechanism of action

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Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase.

Mdm2 selectively suppresses DNA damage arising from inhibition of topoisomerase II independent of p53.

Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters.

p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes.

Peripheral blood mononuclear and tumor cell pharmacodynamics of the novel epothilone B analogue, ixabepilone.

Mutations in beta-tubulin map to domains involved in regulation of microtubule stability in epothilone-resistant cell lines.

Targeting KCC2 and NKCC1 for spinal motor dysfunction: pharmacology, therapeutic opportunities, and translational roadmap.

The regulatory and therapeutic potential of transposable elements in cancer and inflammatory diseases.

The rhythm of pressure: Circadian disruption and chronotherapy.

Drug resistance in cancer: Emerging mechanisms, translational barriers, and pharmacological strategies.

Neuroregulation as a modulatory force in immune checkpoint inhibitor resistance: mechanistic neuro-immune crosstalk informing biomarker-led diagnosis and targetable therapeutic sensitization.

Galectin-3 and its inhibitors: Overview and perspectives.

Synthesis of Chromones with Methylene-Bridged Carbon Substituent via Annulation of o-Hydroxyaryl Enaminones.

Viburnum opulus protects against acetaminophen-induced splenic injury through coordinated antioxidant and anti-inflammatory responses.

The oxysterolome iterative metabolism expands sterol signaling.

New benzylresorcinol and benzylstilbene derivatives from the fruits of orchid Galeola nudifolia Lour. with anti-neuroinflammatory activity.

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Taxol: an antimitotic agent with a new mechanism of action

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