Acute management of serious envenomation by box-jellyfish (Chironex fleckeri)

Two cases of serious envenomation by the northern Australian box-jellyfish (Chironex fleckeri) are reported. The first-aid measures and the subsequent management and follow-up of patients are discussed. In addition to its known life-saving effects, the early administration of the specific antivenom appears to be the best treatment for the savage pain of the sting, and may also result in a reduction of subsequent skin scarring.