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Alprazolam-related digoxin toxicity

G Tollefson, T Lesar, D Grothe

The American Journal of Psychiatry

|December 1, 1984

Abstract:

An elderly woman developed a high serum digoxin concentration resulting in toxicity when alprazolam was added to her digoxin therapy. The reduced renal clearance of digoxin is postulated as the mechanism for this interaction.

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