Related Experiment Video
Updated: Aug 18, 2026

Measurement of Antibody Effects on Cellular Function of Isolated Cardiomyocytes
Published on: March 8, 2013
[Relation between extra- and intracardiac anti-strophanthin properties of anti-arrhythmic agents]
Abstract:
Animal experiments have shown that beta-adrenoblockers have the most marked antistrophanthin properties while antiarrhythmic agents with locally anesthetic attributes are less active. All the substances studied have proved to be ineffective on the cellular model of strophanthin arrhythmia. The data obtained suggest that the antiarrhythmic effect of the substances under study including beta-adrenoblockers is exercised on the level of the receptor apparatus of the postsynaptic membrane. The membrane stabilizing properties do not play the decisive role in ensuring the antiarrhythmic effect in strophanthin arrhythmia.
Related Concept Videos
Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers
Class 1A Antiarrhythmic Drugs: These drugs work by moderately blocking sodium channels,...
Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers
Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers
Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
Heart Failure Drugs: Inotropic Agents
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

