Related Experiment Video

Updated: Jul 12, 2026

Characteristics of Precipitation-formed Polyethylene Glycol Microgels Are Controlled by Molecular Weight of Reactants
11:32

Characteristics of Precipitation-formed Polyethylene Glycol Microgels Are Controlled by Molecular Weight of Reactants

Published on: December 23, 2013

The solubility of 17 beta-oestradiol in aqueous polyethylene glycol 400

M J Groves, B Bassett, V Sheth

    The Journal of Pharmacy and Pharmacology
    |December 1, 1984
    PubMed

    More Related Videos

    A Simple Method for Automated Solid Phase Extraction of Water Samples for Immunological Analysis of Small Pollutants07:26

    A Simple Method for Automated Solid Phase Extraction of Water Samples for Immunological Analysis of Small Pollutants

    Published on: January 1, 2016

    Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology07:05

    Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology

    Published on: August 23, 2024

    Related Concept Videos

    Solubility of Ionic Compounds02:55

    Solubility of Ionic Compounds

    Solubility is the measure of the maximum amount of solute that can be dissolved in a given quantity of solvent at a given temperature and pressure. Solubility is usually measured in molarity (M) or moles per liter (mol/L). A compound is termed soluble if it dissolves in water.
    Physical Properties Affecting Solubility02:19

    Physical Properties Affecting Solubility

    Solutions of Gases in Liquids
    As for any solution, the solubility of a gas in a liquid is affected by the attractive intermolecular forces between solute and solvent species. Unlike solid and liquid solutes, however, there is no solute-solute intermolecular attraction to overcome when a gaseous solute dissolves in a liquid solvent since the atoms or molecules comprising a gas are far separated and experience negligible interactions. Consequently, solute-solvent interactions are the sole...
    Solubility03:00

    Solubility

    Solution, Solubility, and Solubility Equilibrium
    A solution is a homogeneous mixture composed of a solvent, the major component, and a solute, the minor component. The physical state of a solution—solid, liquid, or gas—is typically the same as that of the solvent. Solute concentrations are often described with qualitative terms such as dilute (of relatively low concentration) and concentrated (of relatively high concentration).
    In a solution, the solute particles (molecules, atoms, and/or ions)...
    Factors Affecting Dissolution: Polymorphism, Amorphism and Pseudopolymorphism01:21

    Factors Affecting Dissolution: Polymorphism, Amorphism and Pseudopolymorphism

    Polymorphism refers to the existence of a drug substance in multiple crystalline forms, known as polymorphs. Recently, this term has been expanded to include solvates (forms containing a solvent), amorphous forms (non-crystalline forms), and desolvated solvates (forms from which the solvent has been removed).
    Some polymorphic crystals possess lower aqueous solubility than their amorphous counterparts, leading to incomplete absorption. For instance, the oral suspension of Chloramphenicol, which...
    Factors Affecting Dissolution: Drug pKa, Lipophilicity and GI pH01:21

    Factors Affecting Dissolution: Drug pKa, Lipophilicity and GI pH

    Drug absorption within the gastrointestinal (GI) tract is a complex process influenced by several critical factors, including the site pH, the drug's dissociation constant (pKa), and the drug's lipophilicity. The GI tract exhibits a pH gradient, with an acidic environment in the stomach and a more alkaline environment in the small intestine. This pH variation directly affects the ionization state of drugs.
    A drug's pKa and the pH of the gastrointestinal (GI) tract play crucial roles in drug...
    Bioavailability Enhancement: Drug Solubility Enhancement01:16

    Bioavailability Enhancement: Drug Solubility Enhancement

    Bioavailability is a critical factor in determining a drug's effectiveness. It refers to the proportion of a drug that enters the circulation when introduced into the body and is, as a result, able to have an active effect. Enhancing bioavailability is essential for drugs with poor solubility, as it can significantly impact their therapeutic efficacy. Various methods are employed to increase the solubility of drugs, thereby enhancing their bioavailability.Micronization and nanonization are...