Related Experiment Video
Updated: Aug 11, 2026

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices
Published on: October 6, 2017
Abstract:
It is 25 years since biochemical analysis of neurotransmitters in autopsied human brains was first applied to elucidation of the underlying mechanisms in functional neuronal disorders. In this time this line of research has revealed a selective decrease in catecholamines and of their synthesizing enzyme activities which occur in Parkinson's disease, and has led to the development of L-DOPA replacement therapy. Much attention is now being given to the other neurodegenerative disorders. This paper summarizes recent advances in research on neurotransmitter abnormalities in Parkinson's disease, Huntington's disease and the spinocerebellar degeneration.
More Related Videos
Related Concept Videos
Excitatory and Inhibitory Effects of Neurotransmitters
Neurotransmitters
Disorders of the Nervous Tissue
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Parkinson's Disease: Overview
Neurotransmitters
Role of Neurotransmitters in Memory
Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is critical for...

