Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Scleral calcifications in hyperparathyroidism: demonstration by computed tomography.

C R Kollarits, M L Moss, D G Cogan

    Journal of Computer Assisted Tomography
    |October 1, 1977
    PubMed
    Summary

    Scleral calcifications, deposits of calcium in the eye

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Spontaneous Intracellular Calcium Oscillations and G(s) α Subunit Expression are Inversely Correlated with Secretory Granule Content in Pituitary Cells.

    Journal of neuroendocrinology·2011
    Same author

    Production and purification of human menin from Drosophila melanogaster S2 cells using stirred tank reactor.

    Cytotechnology·2008
    Same author

    Menin molecular interactions: insights into normal functions and tumorigenesis.

    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2005
    Same author

    Bidirectional transcriptional activity of PGK-neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice.

    Genesis (New York, N.Y. : 2000)·2001
    Same author

    The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation.

    Oncogene·2001
    Same author

    Human Ca(2+) receptor extracellular domain. Analysis of function of lobe I loop deletion mutants.

    The Journal of biological chemistry·2001

    Area of Science:

    • Ophthalmology
    • Endocrinology
    • Radiology

    Background:

    • Hyperparathyroidism is a condition involving excess parathyroid hormone.
    • Ocular manifestations of hyperparathyroidism are rare.
    • Scleral calcifications are not a commonly recognized sign.

    Observation:

    • Two patients with hyperparathyroidism and normal eyes showed scleral calcifications on imaging.
    • Computed tomography (CT) revealed calcification in one patient, while plain films also showed it.
    • CT uniquely identified a solitary scleral plaque in the second patient.

    Findings:

    • Histopathology confirmed calcium plaques in the posterior sclera of a third hyperparathyroid patient.
    • The observed calcifications correlate with CT findings.

    Related Experiment Videos

  • This suggests scleral calcification is a potential sign of hyperparathyroidism.

    • Implications:

    • CT imaging may detect subtle scleral calcifications in hyperparathyroidism.
    • Scleral calcification could serve as an indicator for underlying metabolic bone disease.
    • Further research is warranted to understand the prevalence and significance of these findings.