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Murine Model of Allergen Induced Asthma
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Inhalant allergy due to crickets.

A H Bagenstose, K P Mathews, H A Homburger

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    |January 1, 1980
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    Summary
    This summary is machine-generated.

    Occupational exposure to crickets can cause allergic rhinitis and asthma. These conditions are linked to type I hypersensitivity reactions to potent cricket allergens, confirmed by various diagnostic tests.

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    Area of Science:

    • Environmental medicine
    • Allergology
    • Occupational health

    Background:

    • Occupational asthma and allergic rhinitis are significant workplace health concerns.
    • Identifying specific environmental triggers is crucial for diagnosis and prevention.

    Observation:

    • Two employees involved in cricket raising developed symptoms of allergic rhinitis and bronchial asthma.
    • These symptoms were strongly suspected to be occupationally related to their work environment.

    Findings:

    • Diagnostic tests including skin tests, bronchial challenge, radioallergosorbent test (RAST), and in vitro histamine release confirmed type I hypersensitivity.
    • The identified allergens were associated with crickets, indicating cricket emanations as the causative agent.
    • Further testing on other employees and allergy patients suggested cricket emanations are potent allergens.

    Implications:

    • This study highlights crickets as a significant source of occupational allergens.
    • Awareness and diagnostic measures for cricket-related allergies are important in relevant work settings.
    • Further research into cricket allergen composition and management strategies is warranted.