Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A new hypothesis for synaptic modification: an interactive process between postsynaptic competition and presynaptic

Y Hirai

    Biological Cybernetics
    |January 1, 1980
    PubMed
    Summary

    A new algorithm for synaptic modification proposes that postsynaptic competition and presynaptic regulation interact to control changes in neural connections. This competitive rule organizes neural network structures, like one-to-one and many-to-many connections.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Somatic mutations of the PTEN/NMAC1 gene associated with frequent chromosomal loss detected using comparative genomic hybridization in endometrial cancer.

    Gynecologic oncology·2001
    Same author

    Identification of a high-risk subgroup in cytology-positive stage IIIA endometrial cancer.

    Acta cytologica·2001
    Same author

    Characterization of mutant clones lacking T-cell receptor alleles in a cell line from an adult T-cell leukaemia patient.

    British journal of haematology·2001
    Same author

    Positive peritoneal cytology in endometrial cancer: enhancement of other prognostic indicators.

    Gynecologic oncology·2001
    Same author

    Müllerian adenosarcoma of the uterus: report of a case with imprint cytology.

    Acta cytologica·2001
    Same author

    Analysis of E6 variants of human papillomavirus type 33, 52 and 58 in Japanese women with cervical intraepithelial neoplasia/cervical cancer in relation to their oncogenic potential.

    Cancer letters·2001

    Area of Science:

    • Neuroscience
    • Computational Neuroscience
    • Artificial Intelligence

    Background:

    • Synaptic plasticity is crucial for learning and memory.
    • Existing models of synaptic modification often focus on single mechanisms.
    • Recent physiological data suggest a more interactive process.

    Purpose of the Study:

    • To propose a novel hypothesis for synaptic modification based on interactive processes.
    • To introduce a fundamental competitive rule algorithm for synaptic modification.
    • To analyze the performance of this algorithm in organizing neural network structures.

    Main Methods:

    • Developed a new hypothesis integrating postsynaptic competition and presynaptic regulation.
    • Proposed and analyzed a fundamental algorithm for the competitive rule.

    Related Experiment Videos

  • Simulated the algorithm's performance on a digital computer using randomly connected neural networks.
  • Assessed the organization of neural connection configurations after repetitive stimulus presentation.

    • Main Results:

    • The proposed algorithm successfully organizes basic neural connection configurations (one-to-one, one-to-many, many-to-one, many-to-many).
    • The resulting network structures are dependent on the algorithm's parameters.
    • The simulation demonstrated the feasibility of the interactive model.

    Conclusions:

    • An interactive process between postsynaptic competition and presynaptic regulation provides a unified framework for synaptic modification.
    • The proposed competitive rule algorithm effectively shapes neural network architecture.
    • This model offers a new perspective on how neural networks self-organize.