The effect of adaptation to the stimulating pattern on the latency and wave form of visual evoked potentials

Visual evoked potentials (VEPs) elicited with a checkerboard stimulus after adaptation to an unpatterned grey field were compared to those obtained after adaptation to the stimulating pattern for an equal interval of time. When 3--4 sec elapsed between the adapting interval and recording of the VEP, the latency of the principal positive peak increased by 4 msec with pattern-reversal, but not with pattern-onset stimulation, while the amplitude was unchanged. However, when the pattern-onset VEP was recorded immediately after adaptation, the principal negative peak of the response was lost and the latency of its principal positive peak increased by 14 msec, causing it to mimic the conventional pattern-reversal VEP in both wave form and latency, and suggesting that adaptation may cause the wave form differences in the VEPs obtained by these two methods.