Related Experiment Video
Updated: Aug 10, 2026

Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
Published on: April 1, 2022
[Diagnosis and therapy of acute pancreatitis (author's transl)]
Abstract:
In the course of acute pancreatitis an edematous and a hemorrhagic necrotizing pattern have to be discerned. Clinical symptoms are upper abdominal pain, shock, and metabolic derangements. Only subtle diagnostic procedures are appropriate as for instance x-ray of the chest and x-ray of the abdomen. Laboratory exams are of little value. For conservative treatment atropin, glucagon, calcitonin and antibiotics are being used nowadays, where as the efficacy of aprotinin is controversial. In the Department of Surgery of the Freiburg University Medical School an attempt at early surgery is made. In edematous pancreatitis the bursa omentalis is drained; in addition a T-drain has to be entered into the ductus choledochus. Seqmental necrosis of the pancreas may require resection of the left part of the pancreas. Necrotic areas of the head of the pancreas have to be removed by ablation. If there is total necrosis only drainage with an irrigation-suction pattern is possible.
Related Concept Videos
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis II: Clinical Manifestations and Management
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Acute Pancreatitis I: Introduction
Acute Pancreatitis II: Pathophysiology

