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Verruciform xanthoma.

B W Neville, D R Weathers

    Oral Surgery, Oral Medicine, and Oral Pathology
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Verruciform xanthoma (VX) is a rare oral lesion. This report details 21 new cases, increasing the total literature cases to 50, primarily affecting middle-aged individuals in the gingiva or alveolar ridge.

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    Area of Science:

    • Oral Pathology
    • Dermatology
    • Dermatopathology

    Background:

    • Verruciform xanthoma (VX) is a rare, benign oral mucosal lesion.
    • Its etiology remains largely unknown, prompting further investigation into its pathogenesis.
    • Previous literature documented a limited number of cases, necessitating a larger cohort for comprehensive analysis.

    Purpose of the Study:

    • To report an additional 21 cases of verruciform xanthoma.
    • To consolidate existing literature data, reaching a total of 50 reported cases.
    • To analyze the demographic and clinicopathological features of verruciform xanthoma.

    Main Methods:

    • Case review of 21 patients diagnosed with verruciform xanthoma.
    • Compilation and analysis of data from previously published literature.

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  • Statistical analysis of patient age, gender, lesion location, and clinical presentation.

    • Main Results:

    • The study identified 21 new cases, bringing the total reported cases to 50.
    • Verruciform xanthoma predominantly affects middle-aged individuals.
    • The most frequent locations for the lesion are the gingiva and alveolar ridge.

    Conclusions:

    • Verruciform xanthoma is a rare entity with a predilection for the middle-aged population.
    • The gingiva and alveolar ridge are the most common sites for verruciform xanthoma.
    • The underlying cause of verruciform xanthoma remains undetermined and requires further research.