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Urinary beta-thromboglobulin in essential hypertension

J L Anderton, L Fananapazir, J Dawes

    British Journal of Haematology
    |February 1, 1980
    PubMed

    Urinary concentrations of the platelet-specific protein beta-thromboglobulin (beta-TG) were measured in patients with essential hypertension. Values obtained for patients with normal renal function fell within the same population as those for a control group of normal individuals, but nevertheless 21% of these patients had urinary beta-TG values above the upper limit of the normal range. Values for patients with renal insufficiency were significantly different from the other groups, and 44% of these individuals had abnormally elevated urinary beta-TG concentrations. These elevated values may reflect an increased plasma concentration of beta-TG in patients with renal impairment or they could be an indicator of renal damage.

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