Weak susceptibility of rotavirus to bovine interferon in calf kidney cells

Bovine, virus-induced interferon was titred in primary embryonic calf kidney cells, using three challenge viruses: Reovirus type 3, vesicular stomatitis virus (serotype Indiana), and a French isolate of bovine rotavirus (TR) adapted to grow in tissue culture. Rotavirus repeatedly displayed a very weak susceptibility to interferon as compared to the other two viruses.