[Biochemical and immunological characteristics of serum proteins following bone injuries in rats]

The protein, lipo-and glycoprotein components of blood and callus were studied in 145 Wistar rats after fracture of the femur. The injury was associated with the development of hypoproteinemia and disparately oriented shifts in the content of serum fractions: decreasing of the content of albumin and gamma-globulin and elevation of the concentration of chlorine-soluble glucoproteins (seromucoid fraction) and alpha-globulins. The injury did not entail changes in the antigen composition of the serum. However, the content of 5 out of 41 antigens detected fell down significantly. Some of serum proteins were detectable in a 7-day callus.