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[Human celosomias].

A Morin, J H Neidhardt, A D Spanta

    Bulletin De L'Association Des Anatomistes
    |December 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

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    This study classifies celosomia, a congenital anomaly, by examining morphology and organogenesis in embryonic and fetal bodies. Findings detail key characteristics and variations, aiding in understanding and potential treatment of this rare condition.

    Area of Science:

    • Developmental Biology
    • Clinical Anatomy
    • Teratology

    Background:

    • Celosomia, a rare congenital anomaly, lacks a standardized classification system.
    • Understanding its morphology and organogenesis is crucial for diagnosis and treatment.

    Observation:

    • A historical review established a classification system for celosomia.
    • Morphological and organogenetic studies were conducted on 64 embryonic and fetal specimens.
    • Anatomical analysis of 6 human celosomia cases identified constant features, particularly parietal malformations.

    Findings:

    • Anterior (superior), middle (including laparoschisis), posterior (inferior, including bladder exstrophy), and total celosomia types were defined.
    • Posterior celosomia encompasses a spectrum from limited forms to bladder exstrophy.

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  • Total celosomia variants like schistosomia, chelinosomia, and strophosomia represent transitional forms to other complex malformations.

    • Implications:

    • Improved anatomical and organogenetic knowledge enhances treatment possibilities for celosomia.
    • Treatment remains limited for the most severe and complex forms of celosomia.
    • This classification provides a framework for future research and clinical management of celosomia.