Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interventricular septal defect with aortic insufficiency--surgical considerations.

V S Luisi, P Pugliese, S Eufrate

    The Thoracic and Cardiovascular Surgeon
    |June 1, 1980
    PubMed
    Summary

    Early closure of ventricular septal defect (VSD) may prevent or control associated aortic insufficiency (AI). This study reviewed 14 VSD with AI cases, finding no mortality and positive outcomes with timely surgical intervention.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Efficacy and safety of BNT162b2 mRNA vaccine in a cohort of 90 transfusion dependent thalassemia patients.

    Transfusion medicine (Oxford, England)·2024
    Same author

    Proposal of the French HIV Society on the CD4 threshold below which patients living with HIV who wish to be vaccinated against Monkeypox should receive a 3-dose regimen.

    Infectious diseases now·2022
    Same author

    Dramatic decline in new HIV diagnoses in persons born in France in a large nationwide HIV cohort.

    Public health·2021
    Same author

    Impact of COVID-19 on hand surgery in Italy: A comparison between the Northern and the Southern regions.

    Hand surgery & rehabilitation·2020
    Same author

    Kaposi sarcoma among people living with HIV in the French DAT'AIDS cohort between 2010 and 2015.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2020
    Same author

    Too fast to stay on track? Shorter time to first anti-retroviral regimen is not associated with better retention in care in the French Dat'AIDS cohort.

    PloS one·2019

    Area of Science:

    • Cardiology
    • Pediatric Surgery
    • Thoracic Surgery

    Background:

    • Ventricular septal defect (VSD) can be associated with aortic insufficiency (AI).
    • AI in VSD patients can result from endocarditis or cusp prolapse.
    • Understanding the interplay between VSD and AI is crucial for surgical planning.

    Purpose of the Study:

    • To review pathological and surgical aspects of VSD associated with AI.
    • To evaluate surgical outcomes for VSD closure and AI management.
    • To determine optimal timing for surgical intervention in pediatric patients.

    Main Methods:

    • Retrospective review of 14 consecutive cases of VSD with AI.
    • Surgical techniques included VSD closure (Teflon patches, direct suture) and AI management (valve replacement, reconstruction).

    Related Experiment Videos

  • Analysis of pre- and post-operative clinical data, including cardiothoracic ratio and electrocardiogram.

    • Main Results:

    • No mortality observed in the 14 cases.
    • Successful VSD closure achieved in all patients.
    • AI management included valve replacement in one case and reconstruction in six; residual AI resolved in three patients post-operatively.
    • Positive clinical recovery indicated by normalization of cardiothoracic ratio and ECG.

    Conclusions:

    • Early VSD closure, ideally before preschool age, may prevent or mitigate AI progression.
    • Surgical intervention for VSD with AI is safe and effective.
    • Postponing valve replacement in young children is advisable to avoid long-term prosthetic complications, managing AI conservatively when possible.