[Experience in the clinical use of etmozin in different cardiac rhythm disturbances]

The results of treating 95 patients suffering from various disorders of cardiac rhythm with ethmosin are discussed. Sixty-eight patients received oral ethmosin in a daily dose of 600 mg, 12 of them were treated for a long time (85 +/- 39 days on the average), the others for no more than 3--7 days. Fifty patients received a daily dose of 150 mg ethmosin in a single intravenous injection. The therapeutic effect was considered positive if the number of extrasystoles reduced by no less than 50% with complete removal of group extrasystoles and paroxysms of tachycardia according to the data of daily monitoring observation of the ECG and bicycle ergometry. In medication with oral ethmosin a positive effect was achieved in 34 of 55 patients with ventricular extrasystole, in 1 of 5 with atrial extrasystole, in 2 of 5 with paroxysmal tachycardia in the presence of the Wolff--Parkinson--White syndrome, and in 1 patient with paroxysmal atrial tachycardia. In intravenous ethmosin administration ventricular extrasystole was corrected in 12 of 15 patients, atrial in 3 of 6, ventricular tachycardia in 4 of 7, paroxysmal tachycardia with the Wolff--Parkinson--White syndrome in 4 of 5, atrial fibrillation in 1 of 9, atrial tachycardia in 1 of 6; no effect was produced in either of 2 patients with atrial flutter. Oral ethmosin did not produce any side-effects.