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Updated: Jul 15, 2026

The Multifaceted Benefits of Protein Co-expression in Escherichia coli
Published on: February 5, 2015
Protein L4 of the E. coli ribosome regulates an eleven gene r protein operon
Abstract:
We have previously reported autogenous regulation of the S10 operon encoding eleven ribosomal proteins. By measuring the synthesis of individual r proteins after specific oversynthesis of nine different ribosomal proteins from the S10 operon, we now find that one, L4, affects the expression of the operon. Moreover, the induction of L4 synthesis results in a strong reduction of the synthesis of mRNA from at least four genes of the S10 operon.
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Operons
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Inducible Operons: lac Operon
Repressible Operon: trp Operon

