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[Changes in the systemic hemodynamics of patients with chronic cerebrovascular insufficiency]
Insights
This study investigated chronic cerebral circulation insufficiency in 102 patients. Treatment with Rheopolyglucin, antispasmodics, and cardiac glycosides improved blood flow and circulation parameters.
Area of Science:
- Neurology
- Cardiovascular Medicine
- Pharmacology
Background:
- Chronic cerebral circulation insufficiency affects numerous patients, often linked to atherosclerosis and hypertension.
- Understanding hemodynamic disturbances is crucial for effective treatment strategies.
Purpose of the Study:
- To evaluate general hemodynamic parameters in patients with chronic cerebral circulation insufficiency.
- To assess the impact of a specific treatment regimen on cerebral hemodynamics and blood rheology.
Main Methods:
- Hemodynamic parameters were assessed in 102 patients using Evans blue (T-1824) dilution and rheoencephalography.
- Patients had conditions including atherosclerosis and combined atherosclerosis with arterial hypertension.
Main Results:
- All patients exhibited disturbances in general and cerebral hemodynamics.
- These disturbances were more severe in patients with atherosclerosis complicated by arterial hypertension.
- Rheopolyglucin combined with antispasmodics and cardiac glycosides demonstrated a beneficial effect.
Conclusions:
- The combination therapy improved rheological blood properties.
- The treatment positively impacted general and cerebral circulation parameters in patients with chronic cerebral insufficiency.
Abstract:
In 102 patients with chronic cerebral circulation insufficiency (due to atherosclerosis in 70 and atherosclerosis plus arterial hypertension in 32 patients) the general hemodynamic parameters were examined using the method of Evans blue (T-1824) dilution in comparison with rheoencephalographic findings. In all the patients disturbances of the general and cerebral hemodynamics were revealed, these disturbances being more marked in the patients with atherosclerosis complicated with arterial hypertension. Rheopolyglucin combined with antospasmodics and cardiac glycosides was found to produce a beneficial effect on the rheological properties of the blood and the parameters of the general and cerebral circulation.