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Cutaneous crystal cholesterol emboli.

P Deschamps, D Leroy, J C Mandard

    Acta Dermato-Venereologica
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Cholesterol emboli can cause skin lesions like livedo reticularis and gangrene in severe arteriosclerosis patients. Diagnosis requires histopathology showing cholesterol crystals within occluded arterioles.

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    Area of Science:

    • Vascular Medicine
    • Dermatopathology

    Background:

    • Severe arteriosclerosis, particularly of the abdominal aorta, poses risks beyond systemic complications.
    • Atheromatous plaques are a known source of embolic material.

    Observation:

    • A case of cutaneous cholesterol emboli presenting with lower extremity skin lesions is described.
    • Observed lesions include livedo reticularis, nodules, purple toes, ulcerations, and distal gangrene.
    • These manifestations are attributed to microemboli originating from aortic atheromatous plaques.

    Findings:

    • Histopathologic examination is crucial for diagnosis.
    • Microscopic findings reveal arterioles occluded by macrophagic granuloma surrounding cholesterol crystals.
    • This confirms the embolic nature and origin of the cutaneous lesions.

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    Implications:

    • Cutaneous manifestations can be an indicator of severe underlying systemic arteriosclerosis.
    • Early recognition and diagnosis are vital for managing patients with potential embolic events.
    • Understanding this pathway highlights the systemic impact of atherosclerotic disease.