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Specific and non-specific stimulation of unprimed and primed lymphocytes induced by plane-tree allergenic extracts in
Annales D'Immunologie
|March 1, 1980
Abstract:
Whole allergenic extracts (WAE) from plane-tree pollen induces in vitro blastogenesis in splenic lymphocytes from primed and normal rats. Allergen P, the major allergen of plane-tree pollen, induces an early stimulation in primed cells. WAE induced in the same way an early stimulation in primed cells, but a late incorporation of 3H-thymidine occurs at 8 days of culture when lymphocytes from primed or normal rats were used. This late response appears to be non-specific and is not abolished when a short-pulse of antigen is given.