Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

EEG changes in acute viral hepatitis.

G Lanzinger-Rossnagel, B Kommerell

    Electroencephalography and Clinical Neurophysiology
    |October 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Pathological electroencephalograms (EEGs) were found in 15.6% of patients with acute viral hepatitis, unrelated to hepatitis markers or liver function. Drug addiction was significantly more prevalent in those with abnormal EEGs.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Hepatocyte proliferation in primary biliary cirrhosis as assessed by proliferating cell nuclear antigen and Ki-67 antigen labelling.

    Journal of hepatology·1995
    Same author

    Serum levels of adhesion molecules and thrombomodulin as indicators of vascular injury in severe Plasmodium falciparum malaria.

    The Clinical investigator·1994
    Same author

    Soluble tumor necrosis factor receptors in patients with recurrent hepatitis C virus infection after liver transplantation.

    The Clinical investigator·1994
    Same author

    Hepatitis C virus, alcoholic cirrhosis, and hepatocellular carcinoma.

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology·1994
    Same author

    Prevalence and serological manifestation of hepatitis C virus infection in patients with hepatitis non-A, non-B: a follow-up study.

    Presse medicale (Paris, France : 1983)·1994
    Same author

    Plasma kinetics and biliary excretion of colchicine in patients with chronic liver disease after oral administration of a single dose and after long-term treatment.

    Scandinavian journal of gastroenterology·1994

    Area of Science:

    • Neurology
    • Hepatology
    • Clinical Neurophysiology

    Background:

    • Acute viral hepatitis can affect various organ systems, including the central nervous system.
    • Electroencephalography (EEG) is a tool to assess brain activity, but its utility in acute viral hepatitis requires clarification.

    Purpose of the Study:

    • To investigate the prevalence and characteristics of electroencephalographic (EEG) abnormalities in patients with acute viral hepatitis.
    • To determine potential correlations between EEG findings and clinical, laboratory, or demographic factors in this patient group.

    Main Methods:

    • Clinical, biochemical, and electroencephalographic (EEG) examinations were performed on 64 patients with acute viral hepatitis.
    • Patients were categorized based on EEG findings (normal vs. pathological) and analyzed for demographic data, hepatitis markers (HBsAg), drug use, and laboratory values (SGOT, SGPT, bilirubin, prothrombin time).

    Related Experiment Videos

    Main Results:

    • Pathological EEG findings were observed in 19 out of 64 patients (29.7%).
    • No significant difference was found in HBsAg status or age between patients with normal and pathological EEGs.
    • Drug addiction was a significantly more common factor among patients with pathological EEGs (36.8%) compared to those with normal EEGs (8.9%).
    • No direct dependence was found between EEG alterations and liver function tests (SGOT, SGPT, bilirubin, prothrombin time).
    • The majority of pathological EEGs showed generalized slowing with increased theta activity or predominant theta/delta rhythms.
    • After excluding confounding factors like drug use and hypertension, 15.6% of patients still exhibited pathological EEG findings.

    Conclusions:

    • A notable percentage of patients with acute viral hepatitis exhibit subclinical EEG abnormalities.
    • Drug addiction appears to be a significant confounding factor associated with pathological EEGs in this population.
    • Further research is warranted to understand the clinical significance and underlying mechanisms of these EEG changes in acute viral hepatitis.