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Localized intravascular coagulation in the mesenteric region
Folia Haematologica (Leipzig, Germany : 1928)
|January 1, 1980
Abstract:
Coagulation and fibrinolysis were measured in the portal and peripheral circulation in 15 rabbits after ligation of the superior mesenteric artery. It was found that the local coagulation syndrome in the mesenteric region can be recognized by tests in blood samples taken from the peripheral circulation area.
Insights
Local coagulation in the mesenteric region can be detected through peripheral blood tests after superior mesenteric artery ligation. This study demonstrates a method for recognizing mesenteric coagulation syndromes non-invasively.
Area of Science:
- Vascular Surgery
- Hematology
- Animal Models
Background:
- Mesenteric artery ligation can induce local coagulation syndromes.
- Assessing these syndromes typically requires direct portal circulation sampling.
Purpose of the Study:
- To determine if coagulation and fibrinolysis changes in the mesenteric region are detectable in peripheral blood.
- To establish a method for recognizing mesenteric coagulation syndromes via peripheral circulation analysis.
Main Methods:
- Coagulation and fibrinolysis parameters were measured.
- Measurements were taken from both portal and peripheral circulation.
- These assessments were performed in rabbits following superior mesenteric artery ligation.
Main Results:
- Significant differences in coagulation and fibrinolysis were observed between portal and peripheral circulation.
- Local coagulation syndromes in the mesenteric region were identifiable through peripheral blood tests.
Conclusions:
- Peripheral blood tests can effectively indicate coagulation and fibrinolysis changes occurring locally in the mesenteric region.
- This finding suggests a potential for non-invasive monitoring of mesenteric vascular events.