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[Electrocardiographical changes and rhythm disorders in Barlow's syndrome]
Archives Des Maladies Du Coeur Et Des Vaisseaux
|September 1, 1980
Summary
Mitral valve prolapse (MVP) can cause serious cardiac issues, particularly arrhythmias. Holter Monitoring System (HMS) is crucial for detecting these arrhythmias, which often occur during activity.
Area of Science:
- Cardiology
- Electrophysiology
Context:
- Mitral valve prolapse (MVP) is increasingly recognized, affecting 6-8% of the population.
- While often considered benign, MVP can lead to significant cardiac complications, primarily arrhythmias.
Purpose:
- To investigate the incidence of ST changes, heart rate disturbances, QT interval abnormalities, QRS changes, and arrhythmias in MVP patients.
- To evaluate the diagnostic utility of resting ECG, exercise ECG, and Holter Monitoring System (HMS) for arrhythmia detection in MVP.
Summary:
- Echocardiography-confirmed MVP patients showed ventricular repolarization abnormalities in one-third.
- QT interval abnormalities were noted in over 50% of patients.
- HMS detected arrhythmias in 62.5% of patients, significantly more than resting or exercise ECG, with a striking circadian variation and predominance of monomorphic premature ventricular contractions (PVCs).
Impact:
- Holter Monitoring System (HMS) is the preferred method for detecting arrhythmias in MVP patients.
- Understanding arrhythmia patterns aids in elucidating MVP pathogenesis, potentially linking cardiomyopathy and mechanical factors.
- Treatment is indicated for ventricular arrhythmias detected by sensitive methods like HMS, with various antiarrhythmic drugs showing efficacy.