Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The chronaxie time and its practical importance.

W Irnich

    Pacing and Clinical Electrophysiology : PACE
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Chronaxie, a measure of nerve excitability, is crucial for cardiac pacing. Understanding chronaxie optimizes pulse duration, reducing energy consumption and improving safety margins for pacemakers.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Fibrillation threshold induced by alternating current and alternating voltage.

    Biomedizinische Technik. Biomedical engineering·2011
    Same author

    Do gender differences exist in pacemaker implantation?--results of an obligatory external quality control program.

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2009
    Same author

    Do endoscopy capsules interfere with implantable cardioverter-defibrillators?

    Endoscopy·2009
    Same author

    Capsule endoscopy and cardiac pacemakers: investigation for possible interference.

    Endoscopy·2007
    Same author

    Post-mortem evaluation of 415 pacemakers: in situ measurements and bench tests.

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2005
    Same author

    Re: is the optimal tilt really unknown?

    Pacing and clinical electrophysiology : PACE·2001

    Area of Science:

    • Biomedical Engineering
    • Neuroscience
    • Electrophysiology

    Background:

    • Lapicque's rheobase and chronaxie define electrostimulation intensity-duration relationships.
    • These parameters have historically been underutilized in cardiac pacing applications.

    Purpose of the Study:

    • To highlight the significance of chronaxie in cardiac pacing.
    • To demonstrate how chronaxie can optimize pacemaker generator-electrode matching and pacing protocols.

    Main Methods:

    • Mathematical description of intensity-duration curves.
    • Analysis of chronaxie's influence on stimulation parameters.
    • Evaluation of practical implications for cardiac pacing.

    Main Results:

    Related Experiment Videos

  • Chronaxie is influenced by electrode characteristics (size, material) and stimulation mode.
  • Optimal pulse duration should not exceed chronaxie to prevent excessive current consumption.
  • Constant current pacing requires double the pulse duration of constant voltage pacing.
  • Smaller electrodes offer safety advantages by allowing reduced pulse durations.

    • Conclusions:

    • Chronaxie is a vital parameter for efficient and safe cardiac pacing.
    • Knowledge of chronaxie enables precise generator-electrode matching and safety margin estimation.
    • Optimizing pulse duration based on chronaxie reduces energy use and enhances pacing efficacy.