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Benign parotid enlargement in bulimia
Annals of Internal Medicine
|December 1, 1980
Summary
Bulimia nervosa, an eating disorder, can cause temporary, painless swelling of the parotid salivary glands. This swelling typically appears days after binge eating and purging behaviors.
Area of Science:
- Endocrinology
- Gastroenterology
- Psychiatry
Background:
- Bulimia nervosa is characterized by binge eating and compensatory behaviors like self-induced vomiting.
- Parotid gland enlargement is a recognized, though less common, physical manifestation of this disorder.
Observation:
- Seven young women with bulimia nervosa presented with benign, bilateral, and painless parotid enlargement.
- Glandular swelling was intermittent, often appearing 2-6 days post-binge episode cessation.
Findings:
- Associated biochemical findings included hypokalemic alkalosis and elevated serum amylase.
- Parotid gland biopsy in one patient showed normal histology, ruling out other pathologies.
Implications:
- Clinicians should consider bulimia nervosa in patients presenting with unexplained parotid gland enlargement.
- Early recognition of this association can aid in timely diagnosis and management of eating disorders.
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