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The role of antibody multivalency in immune effector processes
Progress in Clinical and Biological Research
|January 1, 1980
Abstract:
The preparation of covalently crosslinked oligomers of antibody molecules is described. It is shown that these oligomers can be used to study quantitatively the effects of multivalency on binding to cell surface Fc receptors. It is also shown that three effector systems differ in the ways in which they interact with multivalent immune complexes.