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Related Experiment Videos

Ureteral motility in sheep.

M Tabatabai, N Cohanim, R Kadivar

    Archives Internationales De Physiologie Et De Biochimie
    |October 1, 1980
    PubMed
    Summary

    Ureteral peristalsis in sheep occurs at 15 waves/min, with decreasing pressure along the ureter. Rapid saline infusion halts this ureteral motility.

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    Area of Science:

    • Physiology
    • Urology
    • Animal Science

    Background:

    • Understanding ureteral motility is crucial for diagnosing and treating urinary tract conditions.
    • Sheep serve as a valuable model for studying mammalian physiology due to anatomical and physiological similarities.

    Purpose of the Study:

    • To characterize the frequency, pressure, and duration of ureteral peristaltic waves in anesthetized sheep.
    • To investigate the effect of induced diuresis on ureteral motility.

    Main Methods:

    • Ureteral motility was assessed in 25 sodium pentobarbital-anesthetized sheep.
    • Peristaltic wave frequency, contraction pressure, and duration were measured.
    • Diuresis was induced via rapid intravenous saline administration.

    Main Results:

    • Mean peristaltic wave frequency was 15 waves/min (range 11-19), consistent throughout the ureter.
    • Mean contraction pressure decreased from the upper (40 cm H2O) to the lower ureter (31 cm H2O).
    • Induced diuresis abolished ureteral peristaltic activity.

    Conclusions:

    • Ureteral peristalsis exhibits a regular frequency but decreasing pressure along its length.
    • Significant diuresis effectively inhibits ureteral motility, suggesting a volume-dependent regulatory mechanism.

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