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Related Experiment Videos

Blood hyperviscosity in psoriasis.

R Wolf, I Machtey, E J Feuerman

    Acta Dermato-Venereologica
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

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    Patients with psoriasis show higher whole-blood viscosity, indicating a potential link between increased blood thickness and vascular disease risk in psoriasis patients.

    Area of Science:

    • Hematology
    • Dermatology
    • Vascular Biology

    Background:

    • Psoriasis is a chronic inflammatory skin condition.
    • Patients with psoriasis have an increased risk of cardiovascular and occlusive vascular diseases.

    Purpose of the Study:

    • To investigate platelet function and whole-blood viscosity in psoriasis patients.
    • To explore potential hemorheological factors contributing to vascular complications in psoriasis.

    Main Methods:

    • Studied 11 patients diagnosed with psoriasis.
    • Measured whole-blood viscosity.
    • Assessed platelet count, platelet aggregation (with ADP, epinephrine, collagen), and platelet malonyldialdehyde.

    Main Results:

    • Whole-blood viscosity was significantly elevated in psoriasis patients (3.33 +/- 0.37 cP) compared to controls (2.80 +/- 0.1 cP).

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  • Platelet count, aggregation, and malonyldialdehyde levels were within normal ranges.

    • Conclusions:

    • Elevated whole-blood viscosity is a notable finding in psoriasis.
    • Increased blood viscosity may be a contributing factor to the higher incidence of occlusive vascular disease in psoriasis patients.