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Platelet-induced retinal neovascularization in leukemia
American Journal of Ophthalmology
|May 1, 1981
Summary
Retinal neovascularization is rare in leukemia, but can occur due to hyperviscosity. In a diabetic patient, this was linked to increased platelets, not leukocytes.
Area of Science:
- Ophthalmology
- Hematology
- Oncology
Background:
- Leukemia can cause retinal changes similar to diabetic or hypertensive retinopathy.
- Retinal neovascularization is an uncommon complication of leukemia.
Observation:
- A 42-year-old woman with diabetes mellitus presented with chronic myelocytic leukemia.
- She developed peripheral retinal neovascularization.
Findings:
- The retinal neovascularization was attributed to hyperviscosity.
- Unlike typical cases, the hyperviscosity was likely caused by an elevated platelet count, not leukocytes.
Implications:
- This case highlights a rare cause of neovascularization in leukemia patients.
- Elevated platelet counts should be considered in the differential diagnosis of hyperviscosity-related complications in leukemia.