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[Viral meningoencephalitis: late development].

L S Cantón, R Estrada González

    Neurologia, Neurocirugia, Psiquiatria
    |January 1, 1977
    PubMed
    Summary

    Most patients infected with ECHO virus 4 showed electroencephalogram (EEG) abnormalities, but most EEGs normalized over time. Clinical central nervous system (CNS) signs were absent, and school progress was minimally affected.

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    [Syphilitic meningoencephalitis; anatomo-clinical study of 4 cases].

    Archivos. Hospital Universitario General Calixto Garcia·1950

    Area of Science:

    • Neurology
    • Virology
    • Pediatrics

    Context:

    • Investigates the long-term neurological sequelae of ECHO virus 4 infection in children.
    • Examines electroencephalogram (EEG) changes following viral central nervous system (CNS) illness.
    • Builds upon a previous evolutive EEG study conducted in 1972-1973.

    Purpose:

    • To assess the persistence and evolution of electroencephalogram (EEG) abnormalities after ECHO virus 4 infection.
    • To correlate EEG findings with clinical neurological status and school performance.
    • To determine the long-term impact of viral meningitis on cerebral electrogenesis.

    Summary:

    • A follow-up study of children with ECHO virus 4 infection revealed that while initial EEG alterations were common, over two-thirds normalized within two years.
    • No significant clinical central nervous system (CNS) signs were observed, and school progress remained largely unaffected.
    • Persistent, though minimal, EEG abnormalities were noted in a small subset of patients, with some exhibiting "irritative" generalized or focal signs.

    Impact:

    • Provides crucial data on the neurodevelopmental outcomes of ECHO virus infections.
    • Highlights the generally favorable prognosis for neurological function despite transient EEG changes.
    • Informs clinical management and parental counseling regarding potential long-term effects of viral CNS infections in children.

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