[Studies on the relation between the uterine contraction and the fetoplacental function (author's transl)]

Uterine contractions were recorded with external tocodynamometer in the 2nd and the 3rd trimesters and their connections with various fetoplacental parameters were studied in view of maternal urinary E3, plasma P-LAP, CAP, E3, AFP and HSAP. The obtained results were summarized as follows; 1) During normal pregnancy, r between uterine contraction and gestational weeks was +0.45 (p less than 0.01). 2) Fetoplacental functions improved as gestational weeks advanced. 3) A relation between any two of the above-mentioned fetoplacental parameters during normal pregnancy was statistically significant except the one between urinary E3 and AFP. 4) The partial coefficient correlation between uterine contraction and urinary E3 was -0.36, while the partial coefficient correlation between gestational weeks and urinary E3 was +0.69. 5) In the threatened abortion or labor, the uterine contractions were more frequent (T0 = 5.4) and the urinary E3 was lower (T0 - 2.2) than in the normal pregnancy. 6) As for the within-day variations, when uterine contractions were frequent, urinary E3 was found decreased (X0 2 = 7.59). 7) Use of beta-2 stimulant lowered plasma E3, but its withdrawal increased the E3 level.