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[Clinical experience with human calcitonin].

G De Bastiani, L Nogarin, R Lazzaretto

    Minerva Medica
    |June 30, 1981
    PubMed
    Summary
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    Synthetic human calcitonin effectively treated various bone diseases, including Paget

    Area of Science:

    • Endocrinology and Bone Metabolism
    • Pharmacology of Bone-Active Agents

    Context:

    • Paget's disease, osteoporosis, and Sudeck's disease are significant bone disorders.
    • Osteolytic metastases and Cooley's anemia present complex clinical challenges.
    • Limited effective treatments necessitate exploration of novel therapeutic agents.

    Purpose:

    • To evaluate the efficacy of synthetic human calcitonin in diverse bone pathologies.
    • To document hematological and biochemical alterations resulting from calcitonin therapy.
    • To assess the clinical response and patient outcomes following treatment.

    Summary:

    • Synthetic human calcitonin was administered to patients with Paget's disease, osteoporosis, Sudeck's disease, osteolytic metastases, and adult Cooley's anemia.
    • Observed blood chemistry changes associated with calcitonin treatment were documented.

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  • A significant majority of patients experienced marked clinical improvement.

    • Impact:

    • Demonstrates the therapeutic potential of synthetic human calcitonin in managing debilitating bone conditions.
    • Highlights calcitonin's role in improving patient quality of life and reducing disease symptoms.
    • Provides evidence for calcitonin as a viable treatment option for complex skeletal disorders.