Effect of intestinal resection in dogs on different digestive parameters

Some aspects of the digestive secretions in intact dogs (Control group) and the same dogs after resections of either 50 or 80% of the small intestine starting from the ileocaecal valve have been studied. In all of the animals the duodenal content flow, duodenal content pH, bile salts and amylase production have been determined; under fasting conditions, response to food (4% fat) and response to cholecystokinin-pancreozymin (CCK-PZ) injection (2 i.u./kg). Our results showed a decrease of pH and amylase production in resected animals, but duodenal content flow and bile salt production were not affected. The increase in duodenal content flow in response to feeding was delayed at onset in resected dogs. The pH and bile salts production were unchanged in response to food and to CCK-PZ injection in all animals, but amylase production decreased in response to food and particularly to CCK-PZ administration in resected animals.