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Visualizing Proteins and Macromolecular Complexes by Negative Stain EM: from Grid Preparation to Image Acquisition
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Visualizing Proteins and Macromolecular Complexes by Negative Stain EM: from Grid Preparation to Image Acquisition

Published on: December 22, 2011

A new en bloc stain for cell membranes: tannic methylamine tungstate

R J Skaer

    Journal of Microscopy
    |July 1, 1981
    PubMed

    Abstract:

    A new stain is described that combines the mordanting and preservative effects of tannic acid with every strong staining, particularly of plasma membranes. The staining is sufficiently intense in some cell types to reveal frequent links between the outer and the inner leaflet of the plasma membrane.

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