Related Experiment Video
Updated: Feb 8, 2026

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
Published on: February 25, 2022
Co-localization of neurophysin- and enkephalin-like immunoreactivity in cat pituitary
Abstract:
Enkephalin and neurophysin immunoreactivity have been co-localized in terminals of frozen-dried cat posterior pituitary, using two methods of immunocytochemistry--the protein A-gold procedure and the PAP method. Absorption controls show reduced staining in all cases. Intermediate lobe cells are negative using the enkephalin and neurophysin antisera, but with alpha-MSH antiserum, posterior lobe terminals are negative and intermediate lobe cells are positive. The data are compatible with the hypothesis that inhibition of release of oxytocin and vasopressin by the pituitary opioid system is accomplished by an autoregulatory mechanism in which the release of enkephalin with oxytocin or vasopressin serves to inhibit release of the neurohormones.
Related Concept Videos
Local Attraction
Hypothalamic-Pituitary Axis
Hormones of the Pituitary Gland
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
The Pituitary Gland
Local Anesthetics: Pharmacokinetics
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...

