[Diffusion in fibrin by simultaneous fibrinolysis]

The distribution kinetics of radioactive 51Cr-EDTA between human plasma and a fibrin coagulation dissolving under the influence of different concentrations of streptokinase is measured by scanning the diffusion tubes point by point.

1. The dissolving rate of the coagulum is temporally constant in great concentrations of streptokinase. 2. The faster the coagulation dissolves, the smaller will be the amount of 51Cr-EDTA diffusing into the coagulum. The analysis of these findings and further calculations confirm the assumption made previously that the diffusion of streptokinase or streptokinase-activator complexes into the coagulum seems to play no essential role in the dissolving rate of the coagulum observed clinically and experimentally.