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[Anti-arrhythmic effectiveness of ethmozine, cordaron and rhythmodan in treating ischemic heart disease]

Kardiologiia
|September 1, 1981
PubMed

Insights

This study evaluated antiarrhythmic drugs like ethmozine, cordarone, and rhythmodan in 127 patients. The treatments showed good efficacy for various cardiac rhythm disorders, including arrhythmias and tachycardia.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Cardiac rhythm disorders, including arrhythmias and tachycardia, affect numerous patients.
  • Effective antiarrhythmic drug therapy is crucial for managing these conditions.

Purpose of the Study:

  • To evaluate the efficacy of ethmozine, cordarone, and rhythmodan in treating diverse cardiac rhythm disorders.
  • To assess the effectiveness of these drugs in patients with conditions such as extrasystoles, tachycardia, and fibrillation.

Main Methods:

  • 127 patients with cardiac rhythm disorders were treated with ethmozine, cordarone, or rhythmodan.
  • Circadian electrocardiography (ECG) using a portable cardiomonitor was performed.
  • Exercise tests, including bicycle ergometry and treadmill tests under ECG monitoring, were conducted.

Main Results:

  • A good therapeutic effect was observed in patients with ventricular and atrial extrasystoles.
  • Effective treatment was noted for paroxysms of supraventricular and ventricular tachycardia, and auricular fibrillation.
  • Cordarone demonstrated particular efficacy in Wolff-Parkinson-White syndrome and supraventricular tachycardia paroxysms.

Conclusions:

  • Ethmozine, cordarone, and rhythmodan are effective in managing a range of cardiac rhythm disorders.
  • Cordarone shows significant promise for treating specific conditions like Wolff-Parkinson-White syndrome and supraventricular tachycardia.

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