Long-term follow-up after pacemaker implantation in sick sinus syndrome

In 74 symptomatic patients suffering from sick sinus syndrome, survival after pacemaker implantation and additional drug therapy was determined. The 5-year survival was poor (47.2%). Evidence of other cardiac disease (present in 44.6%) influenced the prognosis unfavorably, especially in combination with continuing symptoms. As yet the phase of SSS in which chronic cardiac pacing is required, should be considered as a critical stage.