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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
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In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
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Related Experiment Video

Updated: Feb 3, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
08:31

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Published on: October 17, 2025

690

Prostatectomy in patient with leukemia.

H Wilbur, R J Taylor

    Urology
    |December 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Transurethral resection of the prostate (TURP) is a safe procedure for patients with stable leukemia. Preoperative evaluation is crucial to identify risks like leukemic infiltration of the prostate.

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    Area of Science:

    • Urology
    • Hematology
    • Oncology

    Background:

    • Prostatic obstruction is a common issue in elderly men.
    • Leukemia can affect various organs, including the prostate.
    • The safety of surgical interventions in leukemia patients requires careful consideration.

    Purpose of the Study:

    • To evaluate the safety and outcomes of transurethral resection of the prostate (TURP) in patients with leukemia.
    • To assess the incidence of leukemic infiltration in the prostate among these patients.

    Main Methods:

    • Retrospective review of 10 patients with leukemia and prostatic obstruction.
    • All patients underwent routine preoperative evaluation.
    • Transurethral resection of the prostate (TURP) was performed on all patients.

    Main Results:

    • Most patients had chronic lymphocytic leukemia and were in stable condition.
    • Two patients (20%) exhibited leukemic infiltration of the prostate.
    • No undue risks were observed in the cohort undergoing TURP.

    Conclusions:

    • Transurethral resection of the prostate (TURP) can be safely performed in stable leukemia patients.
    • Thorough preoperative assessment is essential for managing patients with leukemia undergoing TURP.
    • Leukemic infiltration of the prostate is a potential finding in this patient group.